Pathologic jaundice is the most serious type of jaundice. When a bilirubin level in your baby’s blood is discovered, it is determined whether or not any treatment is required. The only time you should have your baby’s blood tested is when jaundice develops within 24 hours of birth or when the blood test results are particularly high. In most cases, a bilirubinometer is used to screen newborns for jaundice. It is possible that very high bilirubin levels will affect the baby’s brain cells. The most common cause of jaundice is a genetic condition known as pathological jaundice. However, in some cases, excessive bilirubin levels in a baby’s blood can be harmful. It is not hazardous to have this type of jaundice. The principle distinction between the two conditions is shown in the diagram below. There can be no specific cause of jaundice, but it is always the result of a pathological process. Because of increased hemolysis and the liver’s immaturity, it is impossible to metabolize bilirubin produced during the process in a healthy neonate. A yellowing of the tissues of the body, commonly referred to as jaundice, can be caused by a cholesteal imbalance. Pathological Jaundice can occur in any person, as a result of an ongoing process that interferes with normal biliruba metabolism. A healthy neonate’s jaundice can appear when he or she develops hemolysis, which occurs when the liver does not mature quickly enough to rapidly metabolize bilirubin, and when he or she develops bilirubin resistance. When the mucosal layers of the body yellow, it is considered jaundice. It is caused by the breakdown of excess red blood cells and is not a sign of illness. Physiological jaundice is a yellow discoloration of the skin and whites of the eyes that occurs in newborns. It may be a sign of liver disease, gallbladder disease, or other disorders. Pathological jaundice is a yellow discoloration of the skin and whites of the eyes caused by an accumulation of bilirubin in the blood.
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